Comme Parler Conductivité compex ras Pack à mettre Mécanique facilement
Raf promotes dimerization of the Ras G-domain with increased allosteric connections | PNAS
Structural Insights into the BRAF Monomer-to-dimer Transition Mediated by RAS Binding | bioRxiv
Potential for Next Generation RAS Inhibitors in Adult and Pediatric Cancers
The Ras switch in structural and historical perspective
Simulating Ras: 30 years of progress - NCI
Phosphorylation promotes binding affinity of Rap-Raf complex by allosteric modulation of switch loop dynamics | Scientific Reports
Simulating Ras: 30 years of progress - NCI
Raf promotes dimerization of the Ras G-domain with increased allosteric connections | PNAS
A New Dimension to Ras Function: A Novel Role for Nucleotide-Free Ras in Class II Phosphatidylinositol 3-Kinase Beta (PI3KC2β) Regulation | PLOS ONE
The Activation of RalGDS Can Be Achieved Independently of Its Ras Binding Domain: IMPLICATIONS OF AN ACTIVATION MECHANISM IN Ras EFFECTOR SPECIFICITY AND SIGNAL DISTRIBUTION - ScienceDirect
BRET-based RAS biosensors that show a novel small molecule is an inhibitor of RAS-effector protein-protein interactions | eLife
RAS(ON) Inhibitors | Revolution Medicines
Raf promotes dimerization of the Ras G-domain with increased allosteric connections | PNAS
Simulating Ras: 30 years of progress - NCI
Cancers | Free Full-Text | Cutting the Brakes on Ras—Cytoplasmic GAPs as Targets of Inactivation in Cancer
The Ras switch in structural and historical perspective
Frontiers | The Multi-Level Mechanism of Action of a Pan-Ras Inhibitor Explains its Antiproliferative Activity on Cetuximab-Resistant Cancer Cells
Raf promotes dimerization of the Ras G-domain with increased allosteric connections | PNAS
Pharmaceuticals | Free Full-Text | A Rational Design of α-Helix-Shaped Peptides Employing the Hydrogen-Bond Surrogate Approach: A Modulation Strategy for Ras-RasGRF1 Interaction in Neuropsychiatric Disorders
Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling | Journal of Medicinal Chemistry
Integrated RAS signaling defined by parallel NMR detection of effectors and regulators | Nature Chemical Biology
Mapping the functional versatility and fragility of Ras GTPase signaling circuits through in vitro network reconstitution | eLife
Molecular recognition of RAS/RAF complex at the membrane: Role of RAF cysteine-rich domain | Scientific Reports
Structures of Gα Proteins in Complex with Their Chaperone Reveal Quality Control Mechanisms
The Importance of Mg2+‐Free State in Nucleotide Exchange of Oncogenic K‐Ras Mutants - Pálfy - Chemistry – A European Journal - Wiley Online Library
Mapping the functional versatility and fragility of Ras GTPase signaling circuits through in vitro network reconstitution | eLife
Binding of active Ras and its mutants to the Ras binding domain of PI-3-kinase: A quantitative approach to KD measurements - ScienceDirect
RCSB PDB - 1U8Y: CRystal structures of Ral-GppNHp and Ral-GDP reveal two novel binding sites that are also present in Ras and Rap